Using an RNA-based drug delivered to multiple myeloma blood cancer cells by targeted lipid nanoparticles, researchers at Tel Aviv University (TAU) destroyed 90% of the cells under laboratory conditions and 60% of the cells in human tissues. The researchers developed lipid-based nanoparticles, similar to those used in the COVID-19 vaccine, containing RNA molecules that silence… Read More
Researchers at Tel Aviv University (TAU) have demonstrated for the first time that there is a significant link between behavioral stress and the effectiveness of vaccines. They found that acute stress in mice 9-12 days after vaccination increases antibody response to the vaccine by 70% compared to an unstressed control group. But this comes at… Read More
Researchers at Tel Aviv University (TAU) have identified a method, using experiments and computational tools, to classify two central components of the immune response that operate as a result of severe infectious disease. The discovery provides a doorway to the world of personalized medicine in the field of infectious diseases and the provision of more… Read More
Researchers at Tel Aviv University (TAU) have encoded a toxin produced by bacteria into mRNA molecules and delivered these particles directly to cancer cells. The bacteria caused the cells to produce the toxin, which eventually killed the cancer cells themselves with a success rate of 50%. The groundbreaking study was led by PhD student Yasmin… Read More
Researchers at Tel Aviv University (TAU) and other institutions have developed an innovative gene therapy that may help children suffering from Dravet syndrome (DS). The severe developmental epilepsy results from a mutation not inherited from the parents but occurring randomly in the fetus in a gene called SCN1A. DS manifests as severe epilepsy that is… Read More
A new study conducted at Tel Aviv University (TAU) and the Sheba Medical Center reveals how melanoma cancer cells affect their immediate environment to support their needs. The researchers say that the cells form new lymph vessels in the dermis in order to go deeper into the skin and spread through the body. They believe… Read More
A breakthrough study has demonstrated for the first time that long-lasting memories are consolidated in the human brain through communication between the hippocampus and the cerebral cortex during sleep. The researchers also found that by inducing deep-brain stimulation during sleep, they can improve memory consolidation. The unique study, published on June 1, 2023, in the… Read More
In a study conducted at Tel Aviv University (TAU), the protein CKAP5 (cytoskeleton-associated protein) was used for the first time as a therapeutic target for RNA-based nanodrugs. After identifying a genetically unstable mutation resistant to both chemotherapy and immunotherapy in the tissues of ovarian cancer, the researchers targeted these cells with lipid nanoparticles containing RNA… Read More